Tocris™ Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine

Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry

Brand:  Tocris™ 6913/25

Product Code. 18778916

Description

Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine is a functionalized cereblon ligand for PROTAC™ research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

• Chemical Name or Material: N-[3-[2-[2-(3-Aminopropoxy)ethoxy]ethoxy]propyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-4-yl]oxy]acetamide hydrochloride
• Quantity: 25 mg
• Molecular Formula: C₂₅H₃₄N₄O₉.HCl

• CAS: 2564466-93-7
• Target: Degrader Building Blocks
• Purity: 0.95