Thermo Scientific™ TheraPure™ Bz dA Phosphoramidite

TheraPure™ Bz dA Phosphoramidite is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-2030-75

Product Code. 15658435

Description

• Bz-dA CEP is a phosphoramidite containing 5′ DMT and the nucleoside deoxyadenosine (dA) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
• DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides.
• Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process, and produce the highest amount of full length product.
• Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide.
• The TheraPure trademark denotes a highest level of phosphoramidite purity, developed with the highest stringency of of high definiteion analytics and tightly controlled impurity profiles. Ideal for any therapeutic application.
• Features:
  • Full chemical name: 5′-O-(4,4′-Dimethoxytrityl)-N6-benzoyl-2′-deoxyadenosine-3′-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula: C₄₇H₅₂N₇O₇P
  • Base: dA
  • Base Protection: Bz
  • Formula weight: 857.95 g/mol
  • CAS number: 98796-53-3
  • HPLC Purity: ≥99%; M-11 Impurity ≤0.01%; Single critical impurity ≤0.3%; Presence of dC, dG, or T impurity ≤0.03%
  • 31P NMR Purity: ≥99%; Sum of non-primary peaks at 140-152 ppm: ≤0.3%; No peak(s) above 170 ppm; HMT impurity (∼146ppm): ≤0.10%

Specifications

• Description: 5′-O-(4,4′-Dimethoxytrityl)-N6-benzoyl-2′-deoxyadenosine-3′-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular Weight (g/mol): 857.95 g/mol
• Purity: ≥99%
• Quantity: 100 g