Thermo Scientific™ TheraPure™ Restriction Enzymes

Thermo Scientific TheraPure in vitro transcription (IVT) enzymes are designed for advanced research and early development of mRNA therapeutics and vaccines.

Product Code	Brand	Enzyme	Concentration	Quantity
18416548	Thermo Scientific™ ER023T1	Eam1104I	20 U/μL	150 μL

Description

Thermo Scientific TheraPure in vitro transcription (IVT) enzymes are designed for advanced research and early development of mRNA therapeutics and vaccines. These products offer full workflow solutions from template preparation to RNA synthesis and are recommended for process research and optimization, proof of concept, and preclinical studies.

The high purity of TheraPure IVT enzymes is ensured by precise quality testing that includes confirmation that that the enzymes are nuclease- and endotoxin-free. In addition, the manufacturing process of TheraPure products follows ISO9001 and ISO13485 standards.

Features

• Convenient stand-alone enzymes for easy workflow optimization
• Animal-origin-free (AOF) raw materials used in manufacturing
• No risk of prion or animal virus contamination
• Reproducible and consistent results with validated quality testing
• Regulatory compliant—β-lactam-free manufacturing technology
• Suitable for translational research
• Facilitates transition to GMP during mRNA vaccine development process
• Scalable and available as OEM product

The exceptional quality of TheraPure products is supported by:

• Certificates of analysis
• Certificates of origin
• TSE/BSE statement

Specifications

• Concentration: 20 U/μL
• For Use With (Application): In vitro Transcription
• Methylation Sensitivity: Not Dam Methylation-Sensitive, Not Dcm Methylation-Sensitive, Not CpG Methylation-Sensitive
• Compatible Buffer: 10X Tango Buffer
• Optimal Reaction Temperature: 37°C
• Quantity: 150 μL
• Product Type: Restriction Enzyme
• Product Line: TheraPure™
• Form: Liquid

• Incubator Temperature: 37°C
• Content And Storage: Store at -20°C.
• Enzyme: Eam1104I
• Sensitive to Heat Inactivation: Yes
• Type IIS RE: Yes
• Cut Site: CTCTTC(1/4)^
• Research Category: Drug Development
• Inactivation Temperature: 65°C

For Research Use Only. Not for use in diagnostic procedures.