Thiamine hydrochloride, 99% (dry wt.), may cont. up to 5% water, Thermo Scientific Chemicals

Description

Thiamine hydrochloride plays an important role as a nutrient for carbohydrate metabolism and in nerve function. It finds application as a food-additive to add a brothy/meaty flavor to gravies or soups. It is involved in the preparation of 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazolium chloride. In addition, it finds use in amino acid synthesis in cultured cells, which is present in many classical and serum-free formulations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamine hydrochloride plays an important role as a nutrient for carbohydrate metabolism and in nerve function. It finds application as a food-additive to add a brothy/meaty flavor to gravies or soups. It is involved in the preparation of 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazolium chloride. In addition, it finds use in amino acid synthesis in cultured cells, which is present in many classical and serum-free formulations.

Solubility
Soluble in water, glycerol, ethanol, dimethyl sulfoxide and methanol. Insoluble in benzene, hexane, chloroform and ether.

Notes
Light sensitive and hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 67-03-8
• Molecular Formula: C12H18Cl2N4OS
• Molecular Weight (g/mol): 337.263
• MDL Number: MFCD00012780
• InChI Key: DPJRMOMPQZCRJU-UHFFFAOYSA-M
• Synonym: thiamine hydrochloride, vitamin b1 hydrochloride, thiamine hcl, aneurine hydrochloride, berin, thiamine chloride hydrochloride, trophite, thiamin chloride, thiamine dichloride, thiaminium chloride
• PubChem CID: 6202
• ChEBI: CHEBI:49105
• IUPAC Name: 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride
• SMILES: CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]

• Melting Point: ∼250°C (decomposition)
• Assay Percent Range: 0.99
• Quantity: 100 g
• Beilstein: 3851771
• Sensitivity: Hygroscopic; Light sensitive
• Merck Index: 14,9295
• Solubility Information: Soluble in water,glycerol,ethanol,dimethyl sulfoxide and methanol. Insoluble in benzene,hexane,chloroform and ether.
• Formula Weight: 337.28
• Percent Purity: 99%
• Assay: (dry wt.), may cont. up to 5% water
• Chemical Name or Material: Thiamine hydrochloride

Safety and Handling

Product Identifier

• Thiamine hydrochloride

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2

Hazard Statement

• H319-Causes serious eye irritation.

Precautionary Statement

• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Thiamine hydrochloride

RUO – Research Use Only