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TNFSF8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 17852-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.Specifications
TNFSF8 | |
Polyclonal | |
Unconjugated | |
TNFSF8 | |
CD153, CD30 L, CD30 ligand, CD30L, CD30LG, TNFSF8 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
21949, 683163, 944 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.27 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P32971, P32972 | |
TNFSF8 | |
TNFSF8 Fusion Protein Ag12303 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |