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Tocris Bioscience™ Exendin-4
Potent GLP-1 receptor agonist
Brand: Tocris Bioscience™ 1933/1
279.90 GBP valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
Exendin-4 is a high affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); originally isolated from Heloderma suspectum venom. Exendin-4 potently induces cAMP formation without stimulating amylase release in pancreatic acini. Potentiates glucose-induced insulin secretion in isolated rat islets. Exendin-4 protects against glutamate-induced neurotoxicity, and in a mouse model of metabolic imblance it reduces neuroinflammation and enhances long-term-potentiation.Specifications
| 1 mg |