Tocris Bioscience™ M40

Potent, non-selective galanin receptor antagonist

Brand:  Tocris Bioscience™ 3425/1

Product Code. 18095972

Description

M40 is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) (Cat. No. 2696) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine (Cat. No. 0927) and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM.

Specifications

• Purity: 0.95
• Content And Storage: Store at -20°C
• Quantity: 1 mg