Transferrin Receptor Monoclonal Antibody (T56/14), PE, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MHCD7104

Product Code. 10445663

Description

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Specifications

• Antigen: Transferrin Receptor
• Classification: Monoclonal
• Concentration: 0.1mg/mL
• Dilution: Assay-dependent
• Gene: TFRC
• Gene Alias: 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: ASR
• Gene ID (Entrez): 7037
• Includes: 0.1% Sodium azide
• Content And Storage: 4° C, store in dark
• Format: Tube

• Applications: Flow Cytometry
• Clone: T56/14
• Conjugate: PE
• Formulation: PBS with 4mg/mL BSA, sucrose and 0.1% sodium azide
• Gene Accession No.: P02786
• Gene Symbols: TFRC
• Immunogen: Human CD71
• Quantity: 500 μL
• Primary or Secondary: Primary
• Packaging: 1 Each
• Target Species: Human
• Form: Liquid
• Isotype: IgG1

Analyte Specific Reagent. Analytical and performance characteristics are not established.