(Trifluoromethyl)trimethylsilane, 95%, Thermo Scientific Chemicals

Description

It is employed as a valuable reagent for trifluoromethylation of electrophilic substrates. It is also use an the nucleophilic addition of the trifluoromethyl group to aldehydes and ketones. It generates trifluoromethide with catalytic amounts of F- (TBAF or CsF) and reacts with carbonyl compounds to produce trifluoromethylated alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is employed as a valuable reagent for trifluoromethylation of electrophilic substrates. It is also use an the nucleophilic addition of the trifluoromethyl group to aldehydes and ketones. It generates trifluoromethide with catalytic amounts of F- (TBAF or CsF) and reacts with carbonyl compounds to produce trifluoromethylated alcohols.

Solubility
Soluble in alcohol, THF, ether, dichloromethane, aromatic and aliphatic hydrocarbons. Soluble in water(with white smokes).

Notes
Moisture sensitive. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Specifications

Chemical Identifiers

• CAS: 81290-20-2
• Molecular Formula: C5H11F3Si
• Molecular Weight (g/mol): 156.22
• MDL Number: MFCD00145454
• InChI Key: MTYSDPUZDZURPP-UHFFFAOYSA-N
• Synonym: trifluoromethyl trimethylsilane, trimethyl trifluoromethyl silane, trifluoromethyltrimethylsilane, ruppert's reagent, tms-cf3, tfmtms, silane, trimethyl trifluoromethyl, unii-a009786qpj, trimethylsilyl trifluoromethane, ruppert-prakash reagent
• PubChem CID: 552549
• IUPAC Name: trimethyl(trifluoromethyl)silane
• SMILES: CC(C)(C)[SiH2]C(F)(F)F

• Boiling Point: 54°C to 55°C
• Quantity: 25 g
• Linear Formula: (CH₃)₃SiCF₃
• UN Number: UN1993
• Beilstein: 4241868
• Flash Point: −10°C (14°F)
• Solubility Information: Soluble in alcohol,THF,ether,dichloromethane,aromatic and aliphatic hydrocarbons. Soluble in water(with white smokes).
• Formula Weight: 142.2
• Percent Purity: 98%
• Refractive Index: 1.3305
• Sensitivity: Moisture sensitive
• Density: 0.962
• Chemical Name or Material: (Trifluoromethyl)trimethylsilane

RUO – Research Use Only