Trimethoprim lactate, 98%, Thermo Scientific Chemicals

Description

Trimethoprim, CAS # 738-70-5, is a trimethoxybenzyl-pyrimidine used as an antimicrobial.

A broad spectrum antibiotic

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Trimethoprim is a synthetic pyrimidine analog that binds dihydrofolate-reductase and inhibits the synthesis of folic acid; when paired with sulfamethoxazole, its activity is enhanced

• Trimethoprim has antibacterial and antiprotozoal properties

Applications

• Trimethoprim inhibits the conversion of para-aminobenzoic acid (PABA) to folic acid near the end of the synthesis pathway and can be used to study related effects

• Trimethoprim has been radiolabeled and used to trace routes of infection, and it also has been used experimentally as a fluorescent labeler to quantify dihydrofolate-reductase expression

Specifications

• Type: Trimethoprim Lactate
• Physical Form: Powder
• CAS: 23256-42-0
• Molecular Formula: C17H24N4O6
• MDL Number: MFCD00171722
• Packaging: Plastic Bottle
• Synonym: 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine lactate salt
• Solubility Information: Soluble in water
• InChI Key: IIZVTUWSIKTFKO-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)O.COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
• IUPAC Name: 2-hydroxypropanoic acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
• Molecular Weight (g/mol): 380.401
• PubChem CID: 3084396
• Formula Weight: 380.39
• Percent Purity: 98%
• Quantity: 250 mg
• Chemical Name or Material: Trimethoprim lactate

RUO – Research Use Only