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Trimethylsilyl cyanide, 97%, Thermo Scientific Chemicals

Product Code. 11414157
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Quantity:
5 g
25 g
100 g

Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

Solubility
Miscible with organic solvents.

Notes
Moisture sensitive. Store in a cool place.Incompatible with water, strong oxidizing agents, strong reducing agents, strong acids and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 7677-24-9
Molecular Formula C4H9NSi
Molecular Weight (g/mol) 99.21
MDL Number MFCD00001765
InChI Key LEIMLDGFXIOXMT-UHFFFAOYSA-N
Synonym trimethylsilyl cyanide, cyanotrimethylsilane, trimethylsilanecarbonitrile, trimethylsilylcyanide, silanecarbonitrile, trimethyl, trimethylsilylnitrile, tmscn, trimethyl silane cyanide, trimethylsilylcarbonitrile, tms cyanide
PubChem CID 82115
IUPAC Name trimethylsilylformonitrile
SMILES C[Si](C)(C)C#N

Specifications

Boiling Point 118°C to 119°C
Melting Point 11°C to 12°C
Quantity 100 g
UN Number UN3383
Beilstein 1737612
Flash Point 1°C (33°F)
Solubility Information Miscible with organic solvents.
Formula Weight 99.21
Percent Purity 97%
Odor Almond-like
Refractive Index 1.391
Sensitivity Moisture sensitive
Density 0.783
Chemical Name or Material Trimethylsilyl cyanide
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Product Identifier
  • Trimethylsilyl cyanide
Signal Word
  • Danger
Hazard Category
  • Acute toxicity Category 1
  • LONG-TERM AQUATIC HAZARD Chronic 1
  • Flammable liquid Category 2
Hazard Statement
  • H225-Highly flammable liquid and vapour.
  • H300-Fatal if swallowed.
  • H310-Fatal in contact with skin.
  • H330-Fatal if inhaled.
  • H410-Very toxic to aquatic life with long lasting effects.
  • EUH029-Contact with water liberates toxic gas.
Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
  • MIXTURE LIST-Contains : Trimethylsilyl cyani

RUO – Research Use Only

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