Tocris Bioscience™ UCPH 101

Selective non-substrate EAAT1 inhibitor

Brand:  Tocris Bioscience™ 3490/10

Product Code. 18043972

Description

UCPH 101 is a selective non-substrate inhibitor of EAAT1 (IC50 values are 660, >300000 and >300000 nM for EAAT1, EAAT2 and EAAT3 respectively). Also demonstrates no significant inhibition at EAAT4 or EAAT5 in a patch-clamp electrophysiology assay (at final concentration up to 10 μM).

Specifications

• Chemical Name or Material: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
• Quantity: 10 mg
• Molecular Formula: C₂₇H₂₂N₂O₃

• CAS: 1118460-77-7
• Target: Glutamate (EAAT) Transporter Inhibitors
• Purity: 98%