UNC13A/Munc13-1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55053-1-AP-20UL

Product Code. 16836495

Description

The antibody is specific to UNC13A.

UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion.

Specifications

• Antigen: UNC13A/Munc13-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UNC13A
• Gene Alias: KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A (C. elegans), UNC13A
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23025, 382018
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunoprecipitation
• Concentration: 0.33 mg/mL
• Formulation: 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q4KUS2, Q9UPW8
• Gene Symbols: Unc13a
• Immunogen: Peptide
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human
• Product Type: Antibody
• Isotype: IgG