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Tocris Bioscience™ uPSEM 817 tartrate
Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
£202.00 - £774.00
Specifications
Chemical Name or Material | 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate |
---|---|
CAS | 2341833-14-3 |
Target | Pharmacologically Selective Effector Molecules/PSEM |
Molecular Formula | C16H19N3O.C4H6O6 |
Formula Weight | 419.43 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18759836
|
Tocris Bioscience™
6866/25 |
25 mg |
£774.00
25mg |
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18005742
|
Tocris Bioscience™
6866/5 |
5 mg |
£202.00
5mg |
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Description
Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).Specifications
2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate | |
Pharmacologically Selective Effector Molecules/PSEM | |
419.43 |
2341833-14-3 | |
C16H19N3O.C4H6O6 | |
98% |
Safety and Handling
Recommended Storage : Store at -20°C
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