Valproic acid, sodium salt, Tocris Bioscience™

Description

Histone deacetylase inhibitor

Histone deacetylase inhibitor (IC50 = 400 μM) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases Aα production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.

Specifications

• CAS: 1069-66-5
• Molecular Formula: C8H15NaO2
• Quantity: 100 mg
• Synonym: sodium valproate, sodium 2-propylpentanoate, valproate sodium, valproic acid sodium salt, eurekene, labazene, orfiril, epilim, valproic acid sodium, valerin
• InChI Key: AEQFSUDEHCCHBT-UHFFFAOYSA-M
• SMILES: CCCC(CCC)C(=O)[O-].[Na+]
• IUPAC Name: sodium;2-propylpentanoate
• Molecular Weight (g/mol): 166.196
• PubChem CID: 16760703
• ChEBI: CHEBI:9925
• Formula Weight: 166.19
• Percent Purity: 0.98
• Chemical Name or Material: Valproic acid, sodium salt