VPS39 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA521104

Product Code. 12809252

Description

A suggested positive control is rat liver tissue lysate. PA5-21104 can be used with blocking peptide PEP-1218.

VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6. 5.

Specifications

• Antigen: VPS39
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS39
• Gene Alias: A230065P22Rik; AW743070; hVam6p; KIAA0770; mVam6; OTTMUSP00000023341; OTTMUSP00000023350; PI3K type 3; Pldn; TLP; TRAP1-like protein; vacuolar protein sorting 39 (yeast); vacuolar protein sorting 39 homolog; vacuolar protein sorting 39 homolog (S. cerevisiae); Vam6; Vam6/Vps39-like protein; Vam6P; Vps39; VPS39 HOPS complex subunit; VPS39, HOPS complex subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23339, 269338, 362199
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8R5L3, Q96JC1
• Gene Symbols: VPS39
• Immunogen: An 18 amino acid peptide near the carboxy terminus of human VPS39.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG