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VU 0357017 hydrochloride, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 μM. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 369.89 |
Percent Purity | >98% |
Chemical Name or Material | VU 0357017 hydrochloride |
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