Tocris Bioscience™ WH-4-023

Potent and selective Lck and Src inhibitor; also inhibits SIK

Brand:  Tocris Bioscience™ 5413/50

Product Code. 18706648

Description

WH-4-023 is a potent and selective Lck and Src inhibitor (IC50 values are 2 and 6 nM respectively). Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases. Supports self-renewal of naive hESCs in combination with PD 0325901, CHIR 99021 and SB 590885 .

Specifications

• Purity: >98%
• Quantity: 50 mg
• Molecular Weight (g/mol): 568.67

• Gene Alias: KIN112
• Product Type: WH-4-023
• Inhibitors: WH-4-023

For Research Use Only