YM 022, Tocris Bioscience™

Description

Highly potent, selective non-peptide CCK2 antagonist

Extremely potent and highly selective non-peptide CCK2 silent antagonist (Ki values are 68 pM and 63 nM at CCK2 and CCK1 receptors respectively). Acts in vivo to potently inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation with a long duration of action.

Specifications

Chemical Identifiers

• CAS: 145084-28-2
• Molecular Formula: C32H28N4O3
• Molecular Weight (g/mol): 516.601
• InChI Key: YCXFHPUBGMMWJQ-PMERELPUSA-N
• Synonym: unii-772cp7w12n, 1-2,3-dihydro-1-2'-methylphenacyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl-3-3-methylphenyl urea, 3-3-methylphenyl-1-3r-1-2-2-methylphenyl-2-oxoethyl-2-oxo-5-phenyl-3h-1,4-benzodiazepin-3-yl urea, urea, n-2,3-dihydro-1-2-2-methylphenyl-2-oxoethyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl-n'-3-methylphenyl-, r, urea,n-3r-2,3-dihydro-1-2-2-methylphenyl-2-oxoethyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl-n'-3-methylphenyl, r-n-2,3-dihydro-1-2-2-methylphenyl-2-oxoethyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl-n'-3-methylphenyl-urea, ym022 racemate, d05hyl, gtpl888, ym hplc
• PubChem CID: 122130
• IUPAC Name: 1-(3-methylphenyl)-3-[(3R)-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]urea
• SMILES: CC1=CC(=CC=C1)NC(=O)NC2C(=O)N(C3=CC=CC=C3C(=N2)C4=CC=CC=C4)CC(=O)C5=CC=CC=C5C

• Quantity: 10 mg
• Formula Weight: 516.6
• Percent Purity: >99%
• Chemical Name or Material: YM 022