Zebularine, Tocris Bioscience™

Description

DNA methyltransferase and cytidine deaminase inhibitor

Orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder carcinoma cells. Inhibits cytidine deaminase (Ki ∽ 2 μM); induces differentiation of mesenchymal stem cells into cardiomyocytes.

Specifications

• CAS: 3724-10-5
• Molecular Formula: C8H8O2S
• Quantity: 10 mg
• Synonym: 2-methylthio benzoic acid, benzoic acid, 2-methylthio, o-methylthio benzoic acid, benzoic acid, o-methylthio, 2-methylsulfanyl benzoic acid, 2-methylmercaptobenzoic acid, 2-carboxyphenyl methyl sulfide, acide methyl-s-2-benzoique, 2-methylmercapto benzoic acid, acide methyl-s-2-benzoique french
• InChI Key: LWJQGKJCZOGGPJ-UHFFFAOYSA-N
• SMILES: CSC1=CC=CC=C1C(=O)O
• IUPAC Name: 2-methylsulfanylbenzoic acid
• Molecular Weight (g/mol): 168.21
• PubChem CID: 19498
• Formula Weight: 228.2
• Percent Purity: >99%
• Chemical Name or Material: Zebularine