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  5. Tocris™ 1A-116
  6. 18054522

Tocris™ 1A-116

Rac1 inhibitor; blocks Rac1-P-Rex1 interaction

Brand:  Tocris™ 6701/10

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Product Code. 18054522

  • £194.00 / 10mg

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Description

Description

1A-116 is a Rac1 inhibitor. Reduces intracellular Rac1-GTP levels and blocks Rac1-P-Rex1 interaction in vitro. Exhibits no effect on GTPase activity of closely related Cdc42. Displays antiproliferative, anti-invasive and pro-apoptotic activity in several cancer cell lines. Exhibits antimetastatic activity in vivo. Also restores antiproliferative effects of Tamoxifen (Cat. No. 6342) in resistant breast cancer cell.
Specifications

Specifications

N-(3,5-Dimethylphenyl)-N-[2-(trifluoromethyl)phenyl]guanidine
10 mg
307.31
98%
1430208-73-3
C16H16F3N3
Inhibitor
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