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Tocris™ 1A-116
Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
£194.00 - £771.00
Specifications
| CAS | 1430208-73-3 |
|---|---|
| Molecular Formula | C16H16F3N3 |
| Formula Weight | 307.31 |
| Product Type | Inhibitor |
| Purity | 98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18054522
|
Tocris™
6701/10 |
10 mg |
£194.00
10mg |
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|
18769846
|
Tocris™
6701/50 |
50 mg |
£771.00
50mg |
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Description
1A-116 is a Rac1 inhibitor. Reduces intracellular Rac1-GTP levels and blocks Rac1-P-Rex1 interaction in vitro. Exhibits no effect on GTPase activity of closely related Cdc42. Displays antiproliferative, anti-invasive and pro-apoptotic activity in several cancer cell lines. Exhibits antimetastatic activity in vivo. Also restores antiproliferative effects of Tamoxifen (Cat. No. 6342) in resistant breast cancer cell.Specifications
| 1430208-73-3 | |
| 307.31 | |
| 98% |
| C16H16F3N3 | |
| Inhibitor |
Safety and Handling
Recommended Storage : Store at -20°C