Tocris Bioscience™ 25-Hydroxycholesterol

Antiviral; also α-crystallin (cryAB) chaperone

Brand:  Tocris Bioscience™ 5741/10

Product Code. 18717948

Description

25-Hydroxycholesterol is an antiviral. Stimulates expression of miR-185 microRNA which inhibits the hepatitis C virus life cycle via inhibition of cholesterol biosynthesis and virus cell membrane fusion. Also α-crystallin (cryAB) chaperone (Kd = 10.1 μM). Blocks α-crystallin aggregation and partially reverses cataract formation by binding and stabilizing soluble forms of cryAB in vitro and in vivo.

Specifications

• Description: Cholest-5-ene-3β,25-diol
• CAS: 2140-46-7
• Formula Weight: 402.65
• For Use With (Application): Antiviral Compounds

• Product Type: Inhibitor
• Molecular Formula: C₂₇H₄₆O₂
• Content And Storage: Store at -20°C
• Quantity: 10 mg

For Research Use Only