Tocris Bioscience™ GSK 6853

Potent and selective BRPF1 inhibitor

Brand:  Tocris Bioscience™ 6198/25

Product Code. 18785716

Description

GSK 6853 is a potent and selective BRPF1 inhibitor. Exhibits >1600-fold selectivity for BRPF1 over other bromodomains (pIC50 values by TR-FRET are 8.1, 5.1/4.8 and 4.7/<4.3 for BRPF1, BRPF2/3 and BRD4 BD1/2, respectively).

Negative Control also available.

Specifications

• Chemical Name or Material: N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxybenzamide
• Quantity: 25 mg
• Formula Weight: 409.48

• CAS: 1910124-24-1
• Molecular Formula: C₂₂H₂₇N₅O₃
• Purity: 98%