4-(Dimethylamino)pyridine, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11499923	Thermo Scientific Alfa Aesar A13016.06	5 g
11409933	Thermo Scientific Alfa Aesar A13016.14	25 g
11419933	Thermo Scientific Alfa Aesar A13016.22	100 g

Description

4-(Dimethylamino)pyridine is a useful nucleophilic catalyst for various reactions viz. esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation and Steglich rearrangement. It is also an effective catalyst for transesterification of beta-keto esters and silylation of alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Dimethylamino)pyridine is a useful nucleophilic catalyst for various reactions viz. esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation and Steglich rearrangement. It is also an effective catalyst for transesterification of beta-keto esters and silylation of alcohols.

Solubility
Soluble in methanol, benzene, ethyl acetate, chloroform, methylene chloride, acetone, and acetic acid. Slightly soluble in ether, diisopropyl ether, cyclohexane, hexane, and water.

Notes
Incompatible with strong oxidizing agents and strong acids.

Chemical Identifiers

• CAS: 1122-58-3
• Molecular Weight (g/mol): 122.171
• InChI Key: VHYFNPMBLIVWCW-UHFFFAOYSA-N
• PubChem CID: 14284
• SMILES: CN(C)C1=CC=NC=C1

• Molecular Formula: C7H10N2
• MDL Number: MFCD00006418
• Synonym: 4-dimethylaminopyridine, dmap, 4-dimethylamino pyridine, 4-pyridinamine, n,n-dimethyl, n,n-dimethyl-4-pyridinamine, p-dimethylaminopyridine, pyridine, 4-dimethylamino, ccris 6176, dimethylpyridin-4-ylamine
• IUPAC Name: N,N-dimethylpyridin-4-amine

Specifications

• CAS: 1122-58-3
• Boiling Point: 162°C (50 mmHg)
• Assay Percent Range: 99%
• MDL Number: MFCD00006418
• Beilstein: 110354
• Solubility Information: Soluble in methanol,benzene,ethyl acetate,chloroform,methylene chloride,acetone,and acetic acid. Slightly soluble in ether,diisopropyl ether,cyclohexane,hexane,and water.
• SMILES: CN(C)C1=CC=NC=C1
• Molecular Weight (g/mol): 122.171
• Formula Weight: 122.17
• Chemical Name or Material: 4-(Dimethylamino)pyridine

• Melting Point: 110°C to 113°C
• Flash Point: 124°C (255°F)
• Molecular Formula: C7H10N2
• UN Number: UN2928
• Synonym: 4-dimethylaminopyridine, dmap, 4-dimethylamino pyridine, 4-pyridinamine, n,n-dimethyl, n,n-dimethyl-4-pyridinamine, p-dimethylaminopyridine, pyridine, 4-dimethylamino, ccris 6176, dimethylpyridin-4-ylamine
• InChI Key: VHYFNPMBLIVWCW-UHFFFAOYSA-N
• IUPAC Name: N,N-dimethylpyridin-4-amine
• PubChem CID: 14284
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H301-H310-H314-H318
Toxic if swallowed.
Fatal in contact with skin.
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P262-P264b-P270-P271-P280-P301+P310-P302+P350-P304+P340-P305+P351+P338-P307+P311-P310-P311-P330-P332+P313-P361-P363-P501c

H301+H331-H310-H315-H318-H370

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missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• 4-(Dimethylamino)pyridine

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2
• Acute toxicity Category 3
• LONG-TERM AQUATIC HAZARD Chronic 2
• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity after single exposure Category 1

Hazard Statement

• H301-Toxic if swallowed.
• H310-Fatal in contact with skin.
• H315-Causes skin irritation.
• H318-Causes serious eye damage.
• H331-Toxic if inhaled.
• H370-Causes damage to organs.
• H411-Toxic to aquatic life with long lasting effects.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : 4-(Dimethylamino)pyridine

RUO – Research Use Only