Acetylsalicylic acid, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity	Packaging
10640754	Thermo Scientific Acros 158180500	50 g	Plastic bottle
10032160	Thermo Scientific Acros 158185000	500 g	Plastic bottle
10318893	Thermo Scientific 158180025	2.5 kg	Plastic bottle

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• Acetylsalicylic acid is a common non-steroidal anti-inflammatory (NSAID) and
• Acetylsalicylic acid works by inhibiting cyclooxygenases, reducing prostaglandin production and the release of pyrogens

Applications
• Acetylsalicylic acid is useful for research on fever, postoperative pain, blood clots, and inflammation
• Acetylsalicylic acid may also be used in the study of cancer prevention
• Intended for research use only

Literature references

Levine, G.N.; Bates, E.R.; Bittl, J.A.; Brindis, R.G.; Fihn, S.D.; Fleisher, L.A.; Granger, C.B.; Lange, R.A.; Mack, M.J.; Mauri, L.; Mehran, R.; Mukherjee, D.; Newby, L.K.; O'Gara, P.T.; Sabatine, M.S.; Smith, P.K.; Smith, S.C. Jr. 2016, ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2016, 68(10), 1082-115.

Hoffman, M.K.; Goudar, S.S.; Kodkany, B.S.; Metgud, M.; Somannavar, M.; Okitawutshu, J.; Lokangaka, A.; Tshefu, A.; Bose, C.L.; Mwapule, A.; Mwenechanya, M.; Chomba, E.; Carlo, W.A.; Chicuy, J.; Figueroa, L.; Garces, A.; Krebs, N.F.; Jessani, S.; Zehra F.; Saleem, S.; Goldenberg, R.L.; Kurhe, K.; Das, P.; Patel, A.; Hibberd, P.L.; Achieng, E.; Nyongesa, P.; Esamai, F.; Liechty, E.A.; Goco, N.; Hemingway-Foday, J.; Moore, J.; Nolen, T.L.; McClure, E.M.; Koso-Thomas, M.; Miodovnik, M.; Silver, R.; Derman, R.J. ASPIRIN Study Group. Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial. Lancet. 2020, 25, 395(10220), 285-293.

Chemical Identifiers

• CAS: 50-78-2
• Molecular Weight (g/mol): 180.16
• InChI Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• PubChem CID: 2244
• IUPAC Name: 2-acetyloxybenzoic acid

• Molecular Formula: C9H8O4
• MDL Number: MFCD00002430
• Synonym: aspirin, acetylsalicylic acid, 2-acetoxybenzoic acid, 2-acetyloxy benzoic acid, acetylsalicylate, o-acetylsalicylic acid, o-acetoxybenzoic acid, acylpyrin, polopiryna, easprin
• ChEBI: CHEBI:15365
• SMILES: CC(=O)OC1=CC=CC=C1C(O)=O

Specifications

• CAS: 50-78-2
• CAS Max %: 100.0
• Color: White
• Flash Point: 250°C
• Infrared Spectrum: Authentic
• Molecular Formula: C9H8O4
• MDL Number: MFCD00002430
• Merck Index: 15, 841
• Synonym: aspirin, acetylsalicylic acid, 2-acetoxybenzoic acid, 2-acetyloxy benzoic acid, acetylsalicylate, o-acetylsalicylic acid, o-acetoxybenzoic acid, acylpyrin, polopiryna, easprin
• InChI Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• IUPAC Name: 2-acetyloxybenzoic acid
• PubChem CID: 2244
• Formula Weight: 180.16
• Physical Form: Granular Powder

• CAS Min %: 98.5
• Melting Point: 136.0°C to 140.0°C
• Density: 1.3500g/mL
• Loss on Drying: 0.5% max. (1 g) (vacuum)
• Assay Percent Range: 99%
• Linear Formula: 2-(CH₃CO₂)C₆H₄CO₂H
• Beilstein: 10, 67
• Specific Gravity: 1.35
• Solubility Information: Solubility in water: 3.3g/L (20°C). Other solubilities: 1g in 5mL alcohol,17mL chloroform,,and 10-15 mL ether,slightly soluble in anhydrous ether,decomposes in boiling water,alkali
• SMILES: CC(=O)OC1=CC=CC=C1C(O)=O
• Molecular Weight (g/mol): 180.16
• ChEBI: CHEBI:15365
• Percent Purity: 99%
• Chemical Name or Material: Acetylsalicylic acid

Safety and Handling

GHS H Statement
Harmful if swallowed.

GHS P Statement
IF SWALLOWED: rinse mouth.
Do NOT induce vomiting.
Call a POISON CENTER or doctor/physician if you feel unwell.
Wash face,hands and any exposed skin thoroughly after handling.

GHS Signal Word: Warning

missing translation for 'einecsNumber' : 200-064-1

Product Identifier

• Acetylsalicylic acid

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P264-Wash thoroughly after handling.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only