Amikacin (From Kanamycin A, White Crystalline Powder), Fisher BioReagents

Product Code	Brand	Quantity	Packaging
10134924	Fisher BioReagents BP2643-250	250 mg	Amber Glass
10011313	Fisher BioReagents BP2643-1	1 g	Amber Glass

Description

• An antibiotic that serves as a selective agent to isolate transformed bacteria
• Amikacin functions as an indirect inhibitor of protein synthesis in prokaryotes by binding to the 30S subunit of ribosomes
• Useful as a selective agent to isolate bacteria that have been transformed with plasmid containing the antibiotic-resistant gene
• Intended for research purposes only; not for manufacturing or commercial use

Chemical Identifiers

• CAS: 37517-28-5
• Molecular Weight (g/mol): 585.608
• Synonym: Lukadin
• ChEBI: CHEBI:2637
• SMILES: C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N

• Molecular Formula: C22H43N5O13
• InChI Key: LKCWBDHBTVXHDL-RMDFUYIESA-N
• PubChem CID: 37768
• IUPAC Name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

Specifications

• Type: Amikacin
• CAS: 37517-28-5
• Melting Point: 214°C
• Merck Index: 15, 400
• Synonym: Lukadin
• InChI Key: LKCWBDHBTVXHDL-RMDFUYIESA-N
• IUPAC Name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
• PubChem CID: 37768
• Formula Weight: 585.61
• Chemical Name or Material: Amikacin, From Kanamycin A

• Physical Form: Solid
• pH: 9.5 to 11.5
• Molecular Formula: C22H43N5O13
• Potency: > 900μg/mg
• Solubility Information: completely soluble in water
• SMILES: C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N
• Molecular Weight (g/mol): 585.608
• ChEBI: CHEBI:2637
• Color: White

Safety and Handling

CAUTION!

Emergency Overview
May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Ensure adequate ventilation. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Move to fresh air. If breathing is difficult, give oxygen. Get medical attention immediately if symptoms occur. Do not induce vomiting. Obtain medical attention. Obtain medical attention. .

NFPA

Health:1
Flammability:0
Instability:0

missing translation for 'tsca' : Not on TSCA inventory: for R and D use only; not for manufacturing or commercial purposes.

Recommended Storage : 0° to 5°C, desiccate.

Product Identifier

• Amikacin