Tocris Bioscience™ AZD 8055

Highly potent and selective mTOR inhibitor

Brand:  Tocris Bioscience™ 7840/10

Product Code. 30000023

Description

AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC50 = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC50 values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.

Specifications

• Chemical Name or Material: 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
• Quantity: 10 mg
• Molecular Formula: C₂₅H₃₁N₅O₄

• CAS: 1009298-09-2
• Target: mTOR Inhibitors
• Purity: 0.98