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Tocris Bioscience™ AZD 8055

Highly potent and selective mTOR inhibitor

£101.51 - £360.68

Specifications

Chemical Name or Material 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
CAS 1009298-09-2
Target mTOR Inhibitors
Molecular Formula C25H31N5O4
Purity 0.98
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30000027
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Tocris Bioscience™
7840/50
50 mg
£360.68
50mg
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Estimated Shipment: 05-08-2024
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30000023
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Tocris Bioscience™
7840/10
10 mg
£101.51
10mg
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Estimated Shipment: 05-08-2024
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Description

Description

AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC50 = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC50 values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.
Specifications

Specifications

5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
mTOR Inhibitors
0.98
1009298-09-2
C25H31N5O4
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