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  7. 18706158

Tocris Bioscience™ Bosentan

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Brand:  Tocris Bioscience™ 6232/50

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Product Code. 18706158

  • £291.00 / 50mg

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Description

Description

Bosentan is a high affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C -induced contraction of rat trachea in vitro. Orally bioavailable.
Specifications

Specifications

Antagonist
147536-97-8
551.61g/mol
Non-selective Endothelin Receptor Antagonists
Non-selective Endothelin Receptor
C27H29N5O6S
Store at 4°C
50 mg
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