Tocris Bioscience™ Bosentan

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Brand:  Tocris Bioscience™ 6232/50

Product Code. 18706158

Descripción

Bosentan is a high affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C -induced contraction of rat trachea in vitro. Orally bioavailable.

Especificaciones

• Product Type: Antagonist
• CAS: 147536-97-8
• Formula Weight: 551.61g/mol
• For Use With (Application): Non-selective Endothelin Receptor Antagonists

• Target Proteins: Non-selective Endothelin Receptor
• Molecular Formula: C₂₇H₂₉N₅O₆S
• Content And Storage: Store at 4°C
• Quantity: 50 mg

For Research Use Only