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Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)
Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.
Brand: Thermo Scientific™ 21585
This item is not returnable.
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Description
Thermo Scientific™ Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.
Highlights:
- Crosslink cell-surface proteins before cell lysis and immunoprecipitation
- Identify receptor-ligand interactions by chemical crosslinking
- “Fix” protein interactions to allow identification of weak or transient protein interactions
- Identify near-neighbor protein interactions
- Protein crosslinking to create bioconjugates via single-step reactions
- Immobilize proteins onto amine-coated surfaces
Specifications
Amine-to-Amine | |
Pierce BS3 (Sulfo-DSS), No-Weigh Format | |
No | |
No | |
11.4Å | |
Water |
No | |
Bis(sulfosuccinimidyl) suberate; solid | |
572.43 | |
28mL of typical 1X (1mM) reaction solution (total), or 8 separate uses | |
8 x 2 mg |
For Research Use Only. Not for use in diagnostic procedures.