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CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), NovaFluor™ Red 755, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Invitrogen M036T02R06

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Product Code. 17806872

  • £132.00 / 25µg

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Description

Description

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD274 (PD-L1, B7-H1)
Monoclonal
0.1 μg/Test
PBS with 0.09% sodium azide; pH 7.2
Q9EP73
Cd274
Affinity chromatography
RUO
60533
4° C, store in dark, DO NOT FREEZE!
IgG2a λ
Flow Cytometry
MIH5
NovaFluor Red 755
Cd274
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Rat
25 μg
Primary
Mouse
Liquid
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