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CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), NovaFluor™ Red 755, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Invitrogen M036T02R06
This item is not returnable.
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Description
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.Specifications
CD274 (PD-L1, B7-H1) | |
Monoclonal | |
0.1 μg/Test | |
PBS with 0.09% sodium azide; pH 7.2 | |
Q9EP73 | |
Cd274 | |
Affinity chromatography | |
RUO | |
60533 | |
4° C, store in dark, DO NOT FREEZE! | |
IgG2a λ |
Flow Cytometry | |
MIH5 | |
NovaFluor Red 755 | |
Cd274 | |
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1 | |
Rat | |
25 μg | |
Primary | |
Mouse | |
Liquid |