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Thermo Scientific™ CellSensor™ NFKB-bla Freestyle™ HEK293F Cell Line
Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease.
Brand: Thermo Scientific™ K1663
Description
Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease. The CellSensor™ NFκB-bla FreeStyle™ 293F Cell Line is responsive to tumor necrosis factor alpha (TNFα) and can be used to probe the NFκB signaling pathway. This cell line was validated for DMSO tolerance, incubation time with stimulant and substrate loading conditions. The CellSensor™ NFκB-bla FreeStyle™ 293F Cell Line contains a beta-lactamase reporter gene under the control of NFκB response element. The construct was transduced into FreeStyle™ 293F cells by lentivirus. This cell line is a pool isolated for response to TNFα by flow cytometry. It responds to agonist treatment as expected from literature. Academic and non-profit customers, please inquire for special pricing.
Specifications
Cell-based beta lactamase reporter gene | |
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. | |
CellSensor™ | |
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway | |
CellSensor™ |
Dividing Cells | |
Cytokines, Signaling Pathway | |
1 Vial | |
Dividing Cells | |
Signaling Pathway |
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For Research Use Only. Not for use in diagnostic procedures.