General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ LanthaScreen™ STAT3 GripTite™ Cell Line
The JAK/STAT3 signaling pathway is known to be activated by cytokines such as IL-6. In this pathway, binding of IL-6 to its cell-surface receptors results in the activation of JAKs, which in turn phosphoactivate STAT3 proteins at a specific tyrosine residue (Y705).
Thermo Scientific™ Tango™ EDG7-bla U2OS Cells
Tango™ EDG7-bla U2OS cells contain the human Endothelial Differentiation Gene 7 (EDG7) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ PolarScreen™ Progesterone Receptor Competitor Assay Kit, Red
The PolarScreen™ Progesterone Receptor Competitor Assay Kit, Red, provides a sensitive and efficient method for high-throughput, fluorescence polarization-based screening of potential progesterone receptor (PR) ligands.
Thermo Scientific™ LanthaScreen™ TR-FRET ER alpha Coactivator Assay Kit
The LanthaScreen™ TR-FRET ER alpha Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential estrogen receptor (ER) alpha ligands as agonists or antagonists of ligand-dependent coactivator recruitment.
Thermo Scientific™ LanthaScreen™ ATF2 (19-106) A549 Cell Line
Contains a fusion protein consisting of GFP and a fragment encoding for aa 19-106 of ATF2 under the control of a CMV promotor
Thermo Scientific™ CellSensor™ CRE HEK 293T DA Assay Kit
The CellSensor™ CRE HEK 293T DA (Division Arrested) cells contains a beta-lactamase (bla) reporter gene under control of a cAMP response element (CRE) stably integrated into HEK293T cells.
Thermo Scientific™ GeneBLAzer™ Bradykinin-B2-NFAT-bla CHO-K1 Cells
GeneBLAzer™ Bradykinin-B2-NFAT-bla CHO-K1 cells contain the human Bradykinin Receptor B2 (B2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ M1-bla U2OS Cells
Tango™ M1-bla U2OS cells contain the human muscarinic M1 receptor (CHRM1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ ADRB2-CRE-bla CHO-K1 Cells
The GeneBLAzer™ ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession No. NM_000024.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ RAR alpha DA Assay Kit
The GeneBLAzer™RAR alpha DA (Division Arrested) and RAR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor alpha fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK293T cell line.
Thermo Scientific™ Tango™ OPRL1-bla U2OS Cells
The Tango™ OPRL1-bla U2OS cells contain the human Opioid Receptor-Like 1 (OPRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15 HEK 293T DA Assay Kit
GeneBLAzer™ EDG3-Gα15 HEK 293T DA (Division Arrested) cells and EDG3-Gα15-NFAT-bla HEK 293T cells contain the human EDG3 receptor stably integrated in the GeneBLAzer™ Gα15-NFAT-bla HEK 293T cell line.
Thermo Scientific™ BacMam Akt [pSer473] Cellular Assay Kit
The combination of baculovirus-mediated gene delivery (BacMam) with LanthaScreen™ Cellular Assay technology enables a platform for the analysis of specific posttranslational modifications of various substrates including AKT.
Thermo Scientific™ BacMam Akt [pThr308] Cellular Assay Kit
The combination of baculovirus-mediated gene delivery (BacMam) with LanthaScreen™ Cellular Assay technology enables a platform for the analysis of specific posttranslational modifications of various substrates including AKT.