Cilomilast, MedChemExpress

MedChemExpress Cilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4), with IC50s of ∼100 and 120 nM for LPDE4 and HPDE4, respectively.

Brand:  Medchem Express HY-10790

Product Code. 16435126

Description

Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 (IC50=74, 65, >100, and 83 μM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD).

Specifications

• Chemical Name or Material: Cilomilast
• Color: White
• Molecular Formula: C₂₀H₂₅NO₄
• Synonym: SB-207499
• SMILES: O=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O
• Formula Weight: 343.42
• Grade: Research
• For Use With (Application): COVID-19-immunoregulation

• CAS: 153259-65-5
• Purity Grade Notes: Research
• Quantity: 100 mg
• Solubility Information: DMSO : ≥ 100 mg/mL (291.19 mM)
• Molecular Weight (g/mol): 343.42
• Percent Purity: 99.89%
• Physical Form: Solid

Research purposes only