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Tocris Bioscience™ Covidcil-19

Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency

Brand:  Tocris Bioscience™ 7485/10

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Product Code. 18739256

  • £130.00 / 10mg

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Description

Description

Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by > 3.5 orders of magnitude.
Specifications

Specifications

3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
10 mg
C16H14N4O2
1225177-95-6
Antiviral Compounds
0.98
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