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Tocris Bioscience™ Covidcil-19

Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency

£129.59 - £499.99

Specifications

Chemical Name or Material 3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
CAS 1225177-95-6
Target Antiviral Compounds
Molecular Formula C16H14N4O2
Purity 0.98
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Product Code Brand Quantity Price Quantity & Availability  
18739256
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Tocris Bioscience™
7485/10
10 mg
£129.59
10mg
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18746136
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Tocris Bioscience™
7485/50
50 mg
£499.99
50mg
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Description

Description

Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by > 3.5 orders of magnitude.
Specifications

Specifications

3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
Antiviral Compounds
0.98
1225177-95-6
C16H14N4O2
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