Thermo Scientific Chemicals Cresol Red

Product Code	Brand	Quantity
11483467	Thermo Scientific Chemicals A17243.14	25 g
11493467	Thermo Scientific Chemicals A17243.22	100 g

Description

Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.

Solubility
Soluble in water (slightly at 20°C), 50% ethanol (0.1%), dil. acids, and dil. alkalis. Insoluble in benzene.

Notes
Transition interval (acid): pH 1.8 (orange) to pH 2.0 (yellow); (alkaline) pH 7.0 (yellow) to pH 8.8 (violet)

Chemical Identifiers

• CAS: 1733-12-6
• Molecular Weight (g/mol): 382.43
• InChI Key: OBRMNDMBJQTZHV-UHFFFAOYSA-N
• PubChem CID: 73013
• IUPAC Name: 4-[3-(4-hydroxy-3-methylphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]-2-methylphenol

• Molecular Formula: C21H18O5S
• MDL Number: MFCD00005878
• Synonym: o-Cresolsulfonephthalein
• ChEBI: CHEBI:86218
• SMILES: CC1=CC(=CC=C1O)C1(OS(=O)(=O)C2=CC=CC=C12)C1=CC=C(O)C(C)=C1

Specifications

• Melting Point: >300°C
• Molecular Formula: C21H18O5S
• Beilstein: 343399
• Synonym: o-Cresolsulfonephthalein
• InChI Key: OBRMNDMBJQTZHV-UHFFFAOYSA-N
• IUPAC Name: 4-[3-(4-hydroxy-3-methylphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]-2-methylphenol
• PubChem CID: 73013
• Formula Weight: 382.44

• CAS: 1733-12-6
• MDL Number: MFCD00005878
• Merck Index: 14,2578
• Solubility Information: Soluble in water (slightly at 20°C),50% ethanol (0.1%),dil. acids,and dil. alkalis. Insoluble in benzene.
• SMILES: CC1=CC(=CC=C1O)C1(OS(=O)(=O)C2=CC=CC=C12)C1=CC=C(O)C(C)=C1
• Molecular Weight (g/mol): 382.43
• ChEBI: CHEBI:86218
• Chemical Name or Material: Cresol Red

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

missing translation for 'einecsNumber' : 217-064-2

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only