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Tocris Bioscience™ CY 09

Inflammasomes Inhibitors

Brand:  Tocris Bioscience™ 6436/50

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Product Code. 18791108

  • £706.00 / 50mg

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Description

Description

CY 09 is a NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM).
Specifications

Specifications

4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid
50 mg
98%
1073612-91-5
C19H12F3NO3S2
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