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Tocris Bioscience™ CY 09
Inflammasomes Inhibitors
£196.00 - £706.00
Specifications
| Chemical Name or Material | 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid |
|---|---|
| CAS | 1073612-91-5 |
| Molecular Formula | C19H12F3NO3S2 |
| Purity | 98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18783198
|
Tocris Bioscience™
6436/10 |
10 mg |
£196.00
10mg |
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|
18791108
|
Tocris Bioscience™
6436/50 |
50 mg |
£706.00
50mg |
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Description
NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM).Specifications
| 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid | |
| 1073612-91-5 | |
| C19H12F3NO3S2 | |
| 98% |
Safety and Handling
Recommended Storage : Store at -20°C
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