Epredia™ Lab Vision™ Cyclin D1/Bcl-1, Rabbit Monoclonal Antibody

Obtain accurate and reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Cyclin D1/Bcl-1, Rabbit Monoclonal Antibody.

Product Code	Brand	Form	Quantity
10733436	Epredia™ RM-9104-S0	Concentrated	100 μL
11594564	Epredia™ RM-9104-S1	Concentrated	500 μL
12653687	Epredia™ RM-9104-S	Concentrated	1 mL
12643687	Epredia™ RM-9104-RQ	Ready-to-Use	12 mL

Description

Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).

Host Species: Rabbit

Clone: SP4

Isotype: IgG

Species Reactivity: Human, Mouse, Rat. Others not tested.

Epitope: C-terminus

Immunogen: A synthetic peptide from C-terminus of human cyclin D1

Molecular Weight: 36 kDa

Positive Control: MAD109 cells, breast CA or mantle cell lymphoma

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Specifications

• Antigen: Cyclin D1/Bcl-1
• Applications: Western Blot
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Immunogen: A synthetic peptide from C-terminus of human cyclin D1

• Clone: SP4
• Classification: Monoclonal
• Host Species: Rabbit
• Research Discipline: Cell Cycle
• Primary or Secondary: Primary

Safety and Handling

Product Identifier

• APD Primary Antibody Products, Antibody Diluent

Signal Word

• Danger

Hazard Category

• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P284-¢In case of inadequate ventilation! wear respiratory protection.
• P272-Contaminated work clothing should not be allowed out of the workplace.
• P363-Wash contaminated clothing before reuse.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.