Thermo Scientific™ EZ-Link™ Sulfo-NHS-Biotin

Thermo Scientific™ EZ-Link™ Sulfo-NHS-Biotin is a short-chain, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines.

Brand:  Thermo Scientific™ 21217

Product Code. 11851185

Description

Label antibodies, proteins and other molecules that have primary amines with Thermo Scientific™ EZ-Link Sulfo-NHS-Biotin, a short-chain, water-soluble biotinylation reagent.

• Protein labeling - biotinylate antibodies to facilitate immobilization, purification or detection using streptavidin resins or probes
• Cell surface labeling - biotinylates only surface proteins of whole cells because the negatively charged reagent does not permeate cell membranes
• Amine-reactive - reacts with primary amines (-NH2), such as lysine side-chains or the amino-termini of polypeptides
• Soluble - charged sulfo-NHS group increases reagent water solubility compared to ordinary NHS-ester compounds
• Irreversible - forms permanent amide bonds; spacer arm cannot be cleaved
• Very short - spacer arm (total length added to target) is 13.5 angstroms; it consists of the native biotin valeric acid group only

Specifications

• Description: EZ-Link Sulfo-NHS-Biotin
• Quantity: 50 mg
• Product Line: EZ-Link™
• Chemical Reactivity: Amine
• Solubility: DMF (Dimethylformamide), DMSO (Dimethylsulfoxide), Water
• Spacer: Short

• Product Type: Sulfo-NHS-Biotin
• Content And Storage: Store desiccated at -20°C. Shipped at ambient temperature.
• Cell Permeability: Cell-Impermeant
• Reactive Moiety: Active Ester, Succinimidyl Ester, Sulfo-NHS Ester
• Label or Dye: Biotin
• Label Type: Biotin & Analogs

Safety and Handling

Product Identifier

• EZ-Link Sulfo-NHS-Biotin

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H312-Harmful in contact with skin.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H332-Harmful if inhaled.
• H335-May cause respiratory irritation.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash hands thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : Sulfo-NHS-Biotin

For Research Use Only. Not for use in diagnostic procedures.