Thermo Scientific™ GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 Cells

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells contain the human Adenosine Receptor A2A (ADORA2A) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.

Brand:  Thermo Scientific™ K1530

Product Code. 10626414

Description

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells contain the human Adenosine Receptor A2A (ADORA2A) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells are functionally validated for Z' and EC₅₀ concentrations of NECA. In addition, GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

ADORA2A has been shown to have many roles throughout the body. ADORA2A is involved in pain and inflammation regulation, inhibition of platelet aggregation, blood pressure regulation and contributes to ischemic brain damage. Selective antagonists of the ADORA2A pathway are being tested as adjuvants to dopaminergic drugs to treat Parkinson's disease and schizophrenia.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

Specifications

• Accession Number: NM_000675
• Cell State: Dividing Cells
• Detection Method: Fluorescence
• Gene Symbol: ADORA2A
• Population Status: Single Cell Clone Origin
• Quantity: 2 x 10⁶ Cells
• Target Entry: ADORA2A
• Cell Line: CHO-K1
• Druggable Target: GPCR

• Assay Entry: Cell-based beta lactamase reporter gene
• Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.
  
  Includes:
  • GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells
  • GeneBLAzer™ ADORA2A-CRE-bla CHO-K1
  • Certificate of Analysis
  
  The GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
• For Use With (Application): FRET
• Includes: ADORA2A-CRE-bla CHO-K1 cells, ADORA2A-CRE-bla CHO-K1, Certificate of Analysis
• Product Line: GeneBLAzer™
• Reporter Gene: BLA (Beta-Lactamase)
• Type: Dividing Cells
• System Type: GeneBLAzer™

For Research Use Only. Not for use in diagnostic procedures.