Thermo Scientific™ GeneBLAzer™ ADRB1-CRE-bla CHO-K1 Cells

The GeneBLAzer ™ ADRB1-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-1 Receptor (ADRB1), (Accession No. NM_000684) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.

Brand:  Thermo Scientific™ K1553

Product Code. 10195843

Description

The GeneBLAzer ™ ADRB1-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-1 Receptor (ADRB1), (Accession No. NM_000684) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1129) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).

The ADRB1-CRE-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations of (-) Denopamine. In addition, ADRB1-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.

Specifications

• Accession Number: NM_000684.2
• Cell State: Dividing Cells
• Detection Method: Fluorescence
• Gene Symbol: ADRB1
• Population Status: Pool of Stable Cells
• Quantity: 2 x 10⁶ Cells
• Target Entry: ADRB1
• Cell Line: CHO-K1
• Druggable Target: GPCR

• Assay Entry: Cell-based beta lactamase reporter gene
• Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.
  
  Includes:
  • GeneBLAzer™ ADRB1-CRE-bla CHO-K1 cells
  • GeneBLAzer™ ADRB1-CRE-bla CHO-K1 Assay Protocol
  • Certificate of Analysis
  
  The GeneBLAzer™ ADRB1-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
• For Use With (Application): GPCRs
• Includes: ADRB1-CRE-bla CHO-K1 cells, ADRB1-CRE-bla CHO-K1 Assay Protocol, Certificate of Analysis
• Product Line: GeneBLAzer™
• Reporter Gene: BLA (Beta-Lactamase)
• Type: CHO-K1 Cells
• System Type: GeneBLAzer™

For Research Use Only. Not for use in diagnostic procedures.