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Thermo Scientific™ GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA Assay Kit

The GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA (Division Arrested) cells contain the human Complement Component 5a Receptor 1 (C5AR1) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.

Brand:  Thermo Scientific™ K1544

Product Code. 10531814

  • £630.00 / Each
Estimated Shipment: 04-02-2025
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Description

Description

The GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA (Division Arrested) cells contain the human Complement Component 5a Receptor 1 (C5AR1) (Accession No. NM_000710) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line. GeneBLAzer™ Gα15-NFAT-bla CHO-K1 (Cat. No. K1213) contains a beta-lactamase (bla) reporter gene under control of a NFAT response element and a promiscuous G Protein, Gα15, stably integrated into CHO-K1 cells.

The C5AR1-Gα15 CHO-K1 DA (Division Arrested) cells cells are functionally validated for Z'-factor and EC50 concentrations using C5a. In addition, C5AR1-Gα15-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section. DA cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.

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Thermo Scientific™ GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA Assay Kit > 1 Plate

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