Invitrogen™ GeneBLAzer™ MC2R-CRE-bla-CHO-K1 Cells

GeneBLAzer™ MC2R-CRE-bla-CHO-K1 Cells

Brand:  Invitrogen™ K1483

Product Code. 10702154

Description

The GeneBLAzer™ MC2R-CRE-bla-CHO-K1 cells contain the human melanocortin-2 receptor (MC2R), (Accession # NM_000529.1) and the Melanocortin-2 receptor accessory protein (MRAP), (Accession #NM_178817.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat # K1129) contain a beta-lactamase (bla) reporter gene under control of the cAMP Response Element (CRE).

The MC2R-CRE-bla-CHOK1 cells are functionally validated for Z'-factor and EC50 concentrations of ACTH 1-24. In addition, MC2R-CRE-bla-CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.

Specifications

• Accession Number: NM_000529.2
• Cell State: Dividing Cells
• Detection Method: Fluorescence
• Population Status: Single Cell Clone Origin
• Quantity: 2 x 10⁶ Cells
• Target Entry: MC2R
• Cell Line: CHO-K1
• Druggable Target: GPCR

• Assay Entry: Cell-based beta lactamase reporter gene
• Content And Storage: (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
  Includes:
  o GeneBLAzer ™ MC2R-CRE-bla-CHO-K1 cells
  o GeneBLAzer ™ MC2R-CRE -bla CHO-K1 Assay Protocol
  o Certificate of Analysis
  The GeneBLAzer™ MC2R-CRE -bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
• Gene Symbol: MC2R
• Product Line: GeneBLAzer™
• Reporter Gene: BLA (Beta-Lactamase)
• Type: CHO-K1 Cells
• System Type: GeneBLAzer™

For Research Use Only. Not for use in diagnostic procedures.