Thermo Scientific™ GeneBLAzer™ VPAC2-CRE-bla CHO-K1 Cells

GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells contain the human Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 2 (VPAC2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.

Brand:  Thermo Scientific™ K1706

Product Code. 10093913

Description

CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells are functionally validated for Z' and EC₅₀ concentrations of VIP. In addition, GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

VPAC2 has been implicated in a wide range of autoimmune and inflammation disorders, including Chronic obstructive pulmonary disease, Chronic Fatigue Syndrome. VPAC2 may also play a role in Type-2 diabetes.

Specifications

• Accession Number: NM_003382.3
• Cell State: Dividing Cells
• Detection Method: Fluorescent
• Gene Symbol: VPAC2
• Product Line: GeneBLAzer™
• Target Entry: VPAC2
• System Type: GeneBLAzer™

• Assay Entry: Cell-based beta lactamase reporter gene
• Content And Storage: Contents:
  K1706 GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells
  (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
  Includes:
  • GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells
  • GeneBLAzer™ VPAC2-CRE-bla CHO-K1 Assay Protocol
  • Certificate of Analysis
  
  Storage:
  The GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
• For Use With (Application): FRET
• Population Status: Single Cell Clone Origin
• Reporter Gene: BLA (Beta-Lactamase)
• Cell Line: CHO-K1
• Druggable Target: GPCR

For Research Use Only. Not for use in diagnostic procedures.