Tocris Bioscience™ H 151

STING antagonist

Brand:  Tocris Bioscience™ 6675/10

Product Code. 18717606

Description

H 151 is a STING antagonist. Covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters. Decreases inflammatory cytokine production in human and mouse cells in vitro. Also blocks CMA (Cat. No. 6677) -induced increases in levels of inflammatory cytokines in mice, and alleviates systemic inflammation in a mouse model of autoinflammatory disease.

Specifications

• Chemical Name or Material: N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
• Synonym: ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
• Target: STING Antagonists
• Formula Weight: 279.34

• CAS: 941987-60-6
• Quantity: 10 mg
• Molecular Formula: C₁₇H₁₇N₃O
• Purity: 98%