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Tocris Bioscience™ H 151

STING antagonist

£186.00 - £661.00

Specifications

Chemical Name or Material N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
CAS 941987-60-6
Synonym ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Target STING Antagonists
Molecular Formula C17H17N3O
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18717606
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Tocris Bioscience™
6675/10
10 mg
£186.00
10mg
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18769306
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Tocris Bioscience™
6675/50
50 mg
£661.00
50mg
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Description

Description

  • Covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters
  • Decreases inflammatory cytokine production in human and mouse cells in vitro
  • Also blocks CMA (Cat. No. 6677) -induced increases in levels of inflammatory cytokines in mice, and alleviates systemic inflammation in a mouse model of autoinflammatory disease
Specifications

Specifications

N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
C17H17N3O
98%
941987-60-6
STING Antagonists
279.34
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
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Documents

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